Major Employers
| Employer | Number of Employees |
|---|---|
| Southern Illinois University | 5,870 |
| SIH/Memorial Hospital of Carbondale | 1,713 |
| Neuro Restorative | 400 |
| Walmart Supercenter |
400 |
| Carbondale School Districts 95 and 165 |
361 |
| Illinois Department of Transportation | 293 |
| City of Carbondale | 253 |
| U.S. Postal Service |
188 |
| Copper Dragon Brewing Company |
150 |
| Southern Illinois Regional Social Serv. |
150 |
| Southern Illinoisan |
140 |
| Community Alternatives |
130 |
| Com-Pac International Inc. |
120 |
| Vogler Motor Co. |
120 |
| Buffalo Wild Wings |
110 |
| Schnucks |
110 |
| Auffenberg of Carbondale |
110 |
| Best Buy |
100 |
| Kohl's | 100 |
| Lowe's Home Improvement |
100 |